Fujifilm Diosynth Biotechnologies (FDB) is a global contract development and manufacturing organization (CDMO) with over 25 years of experience in process development and/or manufacturing of greater than 310 molecules at sites in: Billingham, England; Research Triangle Park, North Carolina; and College Station, Texas. At our College Station location, we specialize in the development and manufacture of virus-based vaccines (attenuated or recombinant viruses), oncolytic viral therapies (such as adenovirus, polio) and gene therapy vectors (such as adeno-associated virus [AAV])…
Tag: <span>Vero cells</span>
The Vero cell line is one of the most widely used continuous cell lines in the world, cited in over 10,000 publications. Though originally developed as a host for viral replication, uses for this highly adaptable cell line have expanded far beyond the research laboratory to include diagnostic practices in hospitals, epidemiological surveys, in vitro fertilization clinics, bacterial toxin assays, and vaccine production. ATCC has played a pivotal role in this expansion by distributing the Vero cell line, ATCC® CCL-81™, to the worldwide scientific research community. Recently, ATCC developed a fully-characterized master cell bank of Vero cells prepared under current good manufacturing practice (cGMP) conditions (ATCC® CCL-81.4™). This report traces the history of the Vero cell line from its origins in the laboratory of Dr. Yosihiro Yasumura to its use as a continuous cell substrate for vaccine manufacturing…