Tag: <span>vaccine yield classification</span>

Improving Biopharmaceutical Manufacturing Yield Using Neural Network Classification

Traditionally, the Six Sigma framework has underpinned quality improvement and assurance in biopharmaceutical manufacturing process management. This paper proposes a neural network (NN) approach to vaccine yield classification and compares it to an existing multiple linear regression approach. As part of the Six Sigma process, this paper shows how a data mining framework can be used to extract further value and insight from the data gathered during the manufacturing process, and how insights into yield classification can be used in the quality improvement process.

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Bioinformatics Biologics Biologics Production Research

bioreactor crisp data mining design-of-experiments dm methodologies doe FDA machine learning mvda neural network nn pat pneumococcal vaccine process analytical technology six sigma vaccine yield classification who