Tag: <span>pregnancy vaccine</span>

There are an estimated 225 million cases of malaria each year leading to nearly a million deaths, mostly in children under five years of age. Of the five malaria parasite species that can infect humans Plasmodium falciparum is by far the most virulent, causing 89% of all malaria related deaths in 2008. The P. falciparum parasite escapes the immune system by inserting antigens, functioning as adhesions, into the membrane of the infected erythrocyte. This allows it to sequester in the host microvasculature, thereby avoiding clearance in the spleen…