By Charlotte Dyring, MSc, PhD
Volume 11, Issue 3 (Fall 2012)
There are an estimated 225 million cases of malaria each year leading to nearly a million deaths, mostly in children under five years of age. Of the five malaria parasite species that can infect humans Plasmodium falciparum is by far the most virulent, causing 89% of all malaria related deaths in 2008. The P. falciparum parasite escapes the immune system by inserting antigens, functioning as adhesions, into the membrane of the infected erythrocyte. This allows it to sequester in the host microvasculature, thereby avoiding clearance in the spleen…
Citation: Dyring C. Development of Pregnancy-Associated Malaria Vaccine Using the ExpreS2 Insect Cell Expression System. BioProcess J, 2012; 11(3): 27-34. https://doi.org/10.12665/J113.Dyring
Posted online October 22, 2012