by Daniel Galbraith, PhD
Volume 1, Issue 2 (Summer 2002)
The baculovirus expression system promises to revolutionize the production of recombinant proteins for use as clinical products. The technology is robust, efficient, and low-cost when compared to other cell based systems. The technique may also present an advantage in producing safer products versus the equivalent materials made with mammalian cells. Proteins can be produced in insect cells without animal supplements such as fetal calf serum. In the current climate of concerns over Bovine Spongiform Encephalopathies, and bovine viral risks, this method offers a significant safety, as well as cost advantage, over other production methods…
Citation:
Galbraith D. Regulatory Aspects of Recombinant Protein Products by Baculovirus Expression Systems. BioProcess J, 2002; 1(2): 47-51.