By Stephen Guy, Dave Thomas, Miriam Foster, and Tim Ward
Volume 10, Issue 2 (Winter 2011/2012)
The manual preparation of cell banks in screw-capped cryovials is a slow and labour-intensive process which, due to the sensitivity of cells to the cryopreservation solutions, limits the sizes of batches that can be produced. Manual pipetting and vial-capping tasks increase contamination risks and quality control costs, and raise the likelihood of strain and repetitive motion injuries amongst laboratory staff. TAP Biosystems set an objective to create an automated system for reducing manual processing steps while increasing throughput, and maintaining the same or better sample quality over existing manual processes. Significant improvements have been achieved in tube processing times, reproducibility of filling volumes, and QC costs — all of which are described in this paper…
Citation: Guy S, Thomas D, Foster M, Ward T. Optimizing Production of Cell Banks Using an Automated Cryovial Processor. BioProcess J, 2011; 10(2): 10-13. https://dx.doi.org/10.12665/J102.Guy
Posted online December 22, 2011