Tag: <span>sialylation</span>

A Novel Human Expression System for Generating Glycoprotein with Higher Activity, Fully Human Glycosylation, and Optimised Sialylation

Today concentrated efforts are underway to improve the bioactivity of therapeutic proteins with the aim of reducing: (i) the number and concentration of the applied doses of the therapeutic protein, (ii) undesired side effects, and (iii) the cost of a therapy. A very promising strategy is to optimise the glycosylation of these biotherapeutics. A novel expression platform, GlycoExpress™, has been developed to produce proteins with fully human glycosylation, optimised sialylation, and improved bioactivity…

Read MoreA Novel Human Expression System for Generating Glycoprotein with Higher Activity, Fully Human Glycosylation, and Optimised Sialylation

Biologics Production

bioactivity expression glycosylation optimization scale-up sialylation therapeutic proteins