by Monica Cardona
Volume 6, Issue 1 (Spring 2007)
Enriched or pure oxygen is increasingly being used to improve mammalian and microbial cell culture productivity. Sterilizing filtration of the process gas stream is required to remove all microbial contaminants. The filters used to sterilize the gas stream must meet demanding requirements. They must be capable of withstanding sterilization and integrity testing after each use. Oxygen challenges filters because filter components may suffer corrosion and filter materials can potentially ignite under extreme conditions. So the components of filters used with pure oxygen should be tested and rated for pure oxygen service. This article will delve into the main issues involved in sterilizing enriched or pure oxygen gas streams…
Citation:
Cardona M. Filtration of Enriched and Pure Oxygen Key to Increasing Cell Culture Application Yield. BioProcess J, 2007; 6(1): 46-49. http://dx.doi.org/10.12665/J61.Cardona