By Eric S. Langer
Volume 9, Issue 2 (Winter 2010/2011)
Economic conditions are driving a greater demand for improvements in productivity, cost management, and outsourcing. Technology also continues to advance and change the biomanufacturing environment. This was documented in the recently released 2010 7th Annual Report and Survey of Biopharmaceutical Manufacturing with input provided by 327 biomanufacturers globally. “Productivity improvements” is the #1 area where companies have been focusing on resources this year. The survey also documents an evolutionary change in the basic approaches and technologies used for upstream bioprocessing. While in recent years, the industry has largely been dominated by fed batch (or batch fed) bioprocessing, with fermentation performed in a bioreactor containing the same medium until ready for harvest, the BioPlan survey shows a definite shift towards greater acceptance and use of perfusion bioprocessing…
Citation: Langer ES. Perfusion Bioreactors Are Making a Comeback, But Industry Misperceptions Persist. BioProcess J, 2011; 9(2): 49-52. https://dx.doi.org/10.12665/J92.Langer
Posted online February 9, 2011