by Shauna M. McKelvey and Richard A. Murphy
Volume 9, Issue 1 (Summer 2010)
Filamentous fungi are an important class of organisms with significant commercial importance in the biotechnology sector. Those that dominate the markets and are deemed the most important include: Aspergillus, Penicillium, and Trichoderma. They have become indispensable for the production of enzymes due to their exceptionally high capacity to express and secrete proteins. In addition, recent advancements in genomics have allowed for the sequencing or partial sequencing of many of these species. The significance of these fungi and their associated enzymes has accelerated interest in understanding the mechanisms involved in the regulation of gene expression, primarily through the characterisation of the transcriptional elements involved…
Citation:
McKelvey SM, Murphy RA. Hydrolytic Enzyme Production by Aspergillus niger in Solid State Fermentation: Stimulation of Transcriptional Regulation Through Carbon and Nitrogen Supplementation. BioProcess J, 2010; 9(1): 38-49. http://dx.doi.org/10.12665/J91.McKelvey