Characterization of a Transgenic Murine Antibody Expressed in Nicotiana tabacum Plants

by Déborah Geada et al.
Volume 6, Issue 4 (Winter 2007)

Despite the existence of effective vaccines against Hepatitis B virus, the infection with it remains an important problem worldwide due to its association with hepatocellular carcinoma. Several procedures have been used to purify the Hepatitis B surface antigen (HBsAg) for immunization purposes. Immuno-purification using HBsAg-specific murine monoclonal antibodies (MAbs) has been one of the most successful strategies for such a purpose due to the high antigen selectivity (high affinity) of MAbs…

Citation:
Geada D et al. Characterization of a Transgenic Murine Antibody Expressed in Nicotiana tabacum Plants. BioProcess J, 2007; 6(4): 20-30. http://dx.doi.org/10.12665/J64.Geada